Feline lymphoma originates from a type of white blood cell called the lymphocyte. There are three types of lymphoma, multicentric, which affects the lymph nodes,
alimentary, or GI lymphoma, and mediastinal, which originates in the chest. Multicentric and mediastinal lymphoma is associated with the Feline Leukemia
Virus and Feline Immunodeficiency Virus.
The first symptoms that appear are pretty nonspecific; lethargy, anorexia, weight loss, depression, and sometimes increased thirst and urination. Then, depending on what type of lymphoma is present, more specific symptoms will occur, such as vomiting and diarrhea with the GI lymphoma, and fluid build-up resulting in difficulty breathing with mediastinal lymphoma.
Diagnosis is made with lymph node or organ biopsy. Other tests can be used such as blood tests, x-rays, abdominal ultrasound, CT, and bone marrow testing.
Treatment mainly consists of weekly chemotherapy using an IV catheter and steroids. As with dogs, chemotherapy gives the best prognosis and any concurrent illness or older cat results in a less favorable outcome. It is very
important to add pain management to the treatment to keep your cat comfortable.
Please be mindful of your cat’s overall quality of life. Start making end of life care decisions and plan for in-home euthanasia before your cat is suffering.